OS GSO ISO 23921:2022
ISO 23921:2020
Omani Standard
Current Edition
·
Approved on
10 October 2022
Cigarettes — Determination of tobacco specific nitrosamines in mainstream cigarette smoke with an intense smoking regime — Method using LC-MS/MS
OS GSO ISO 23921:2022 Files
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OS GSO ISO 23921:2022 Scope
This document specifies a method for the quantification of four tobacco specific nitrosamines (TSNAs) in the total particulate matter of cigarette mainstream smoke with the intense smoking regime specified in ISO 20778 by using reversed phase high performance liquid chromatography with tandem mass spectrometry (LC-MS/MS). The quantified TSNAs are: N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N-nitrosoanabasine (NAB) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
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